Irritable bowel syndrome with diarrhoea (IBS-D) and functional diarrhoea (FDr) are the two major functional bowel disorders characterized by diarrhoea. United European Gastroenterology and European Society for Neurogastroenterology and Motility published the new clinical guideline “Functional bowel disorders with diarrhoea”.

Main author: Edoardo Savarino, Fabiana Zingone

Comments: first published: 13 June 2022

Brief description of the initiative: The guidelines will provide guidance on the most effective treatment and management of patients with FI. By providing this information, we specifically aim to improve treatment outcomes and patient satisfaction. The development of the guideline will be based on internationally recognized guideline development methodology. These include criteria of quality, as detailed in the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument, primary methodological research and evaluation undertaken by the guideline development group (GDG).

Support/Lead: Support
Main author: Sadé Assmann, Daniel Keszthelyi
Comments: first published March 2022

Brief description of the initiative: Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and prognosis. A Delphi consensus was initiated with 41 experts from 22 European countries who conducted a literature summary and voting process on 87 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation (GRADE) criteria. Consensus (defined as >80% agreement) was reached for 36 statements.

These guidelines were developed with the support of a UEG Activity Grant.
This article is published simultaneously in United European Gastroenterology Journal and Neurogastroenterology and Mobility.

Support/Lead: Support
Main author: Wauters, L., Dickman, R., Drug, V., Mulak, A., Serra, J., Enck, P., Tack, J., , Accarino, A., Barbara, G., Bor, S., Coffin, B., Corsetti, M., De Schepper, H., Dumitrascu, D., Farmer, A., Gourcerol, G., Hauser, G., Hausken, T., Karamanolis, G., Keszthelyi, D., Malagelada, C., Milosavljevic, T., Muris, J., O’Morain, C., Papathanasopoulos, A., Pohl, D., Rumyantseva, D., Sarnelli, G., Savarino, E., Schol, J., Sheptulin, A., Smet, A., Stengel, A., Storonova, O., Storr, M., Törnblom, H., Vanuytsel, T., Velosa, M., Waluga, M., Zarate, N. and Zerbib, F. (2021)

Comments: published 29. September 2021

Brief description of the initiative: A guideline will be developed to define the clinical indications, performance and rational interpretation of breath tests (H2, CH4 and 13C-breath tests) in adult and paediatric patients. The topic of the guideline will address, in large part functional bloating and diarrhoea. Specifically, it will provide recommendations for the use of breath tests in the evaluation of patients with these symptoms, which are a very common reason for attendance in gastroenterological and in general medical practices.

Support/Lead: Support

Main author: Heinz Hammer, Jutta Keller

Comments: First published: 25 August 2021

Brief description of the initiative: The guidelines will provide guidance on the most effective treatment and management of patients with FI. By providing this information, we specifically aim to improve treatment outcomes and patient satisfaction. The development of the guideline will be based on internationally recognized guideline development methodology. These include criteria of quality, as detailed in the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument, primary methodological research and evaluation undertaken by the guideline development group (GDG).

Support/Lead: Lead

Main author: Paul Enck, Jan Tack

Comments: 2 guidelines in press

Chicago Classification v4.0 (CCv4.0) is the updated classification scheme for esophageal motility disorders using metrics from high-resolution manometry (HRM). Fifty-two diverse international experts separated into seven working subgroups utilized formal validated methodologies over two-years to develop CCv4.0.

Support/Lead: Support
Main author:
Comments:

Achalasia is a primary motor disorder of the oesophagus characterised by absence of peristalsis and insufficient lower oesophageal sphincter relaxation. With new advances and developments in achalasia management, there is an increasing demand for comprehensive evidence-based guidelines to assist clinicians in achalasia patient care.

Authors: RAB Oude Nijhuis, G Zaninotto, S Roman, GE Boeckxstaens, P Fockens, MW Langendam, AA Plumb, AJPM Smout, EM Targarona, AS Trukhmanov, BLAM Weusten, and AJ Bredenoord

Comments: First Published February 5, 2020

These guidelines clear up some common statements and believes on a widespread clinical condition such as functional constipation in adult patients.

Main Authors: L Brusciano, G Gualtieri, C Gambardella

Comments: First published June 9, 2020

Chronic constipation is a common disorder with a reported prevalence ranging from 3% to 27% in the general population. Several management strategies, including diagnostic tests, empiric treatments, and specific treatments, have been developed.

Main Authors: Jordi Serra, Daniel Pohl, Fernando Azpiroz, Giuseppe Chiarioni

Comments: First published November 22, 2019

Anorectal disorders such as dyssynergic defecation, fecal incontinence, levator ani syndrome, and solitary rectal ulcer syndrome are common, and affect both the adult and pediatric populations. Although they are treated with several treatment approaches, over the last two decades, biofeedback therapy using visual and verbal feedback techniques has emerged as an useful option. Because it is safe, it is commonly recommended. However, the clinical efficacy of biofeedback therapy in adults and children is not clearly known, and there is a lack of critical appraisal of the techniques used and the outcomes of biofeedback therapy for these disorders.

Main Authors: S. S. C. Rao,  M. A. Benninga, A. E. Bharucha, G. Chiarioni, C. Di Lorenzo, W. E. Whitehead

Comments: First published April 01, 2015